Hey, that's a great leg! The thigh looks great, the bones are 'straight', the finish is smooth ready for the next layer...what more could you desire? I cover the trousers in the next installment, so if it's easier for you, you could do this leg alone then, and then bulk up and dress the other one afterwards. If I had to suggest you change anything right now, it would be to thin the ankle a little? currently his leg sort of goes into his shoe. I can see the ridge where you've marked out the hem of the trouser leg, just maybe when you add detail for the sock, that extra layer of putty could make them a little thick? Overall though, looking good. It would be nice to have some other views of the armature as you're sculpting it. You have to get your head out of the 2d world and into the 3d one - if something doesn't look right from every angle, then change it, even if that means changing the way he looks slightly from the side like this - it was one of the best pieces of advice I was ever given about sculpting, in relation to faces, but it applies to pretty much everything we do - always continuously move the model. Turn it, view it from different angles after every stroke. It slows you down a tad, but it gives you a better result! As for the other leg impeding this one, it could, you're right. It depends on what tools you're using as to how much of an impediment that would be.
I hope somehting in that random conglomoration of thoughts was useful to you, I love this guy's pose, it'll be great to see him finished!
James